Glutamine is the most abundant amino acid in the body. comprising more than 60 % of the free amino acid pool in skeletal muscle and greater than 20% of total circulating amino acids. Supplemental L-Glutamine may help reduce muscle soreness and rebuild muscle tissue. A loss of glutamine during exercise may be a signal for protein carabolism (muscle breakdown) Glutamine supplementation has been suggested to prevent the loss of body mass through the positive role glutamine plays in protein synthesis and action as a potent anabolic agent when muscle glutamine levels are restored and in a positive nitrogen muscle. synthesis can return to normal rate.